
In a treatise called On the difference between spirit and soul, Qusta ibn Luqa (864-923) wrote that people who want to remember look upwards because this raises the worm-like particle, opens the passage, and enables the retrieval of memories from the posterior ventricle. People who want to think, on the other hand, look down because this lowers the particle, closes the passage, and protects the spirit in the middle ventricle from being disturbed by memories stored in the posterior ventricle (Constantinus Africanus 1536, p. 310)
DESCARTES
“I suppose the body to be nothing but a statue or machine made of earth, which God forms with the explicit intention of making it as much as possible like us” (AT XI:120, CSM I:99).
MEMORY:
The pores or gaps lying between the tiny fibers of the substance of the brain may become wider as a result of the flow of animal spirits through them.

MOVEMENT:
He thought that there are two types of bodily movement. First, there are movements which are caused by movements of the pineal gland. The pineal gland may be moved in three ways: (1) by “the force of the soul,” provided that there is a soul in the machine; (2) by the spirits randomly swirling about in the ventricles; and (3) as a result of stimulation of the sense organs.

SOUL:
“We need to recognize that the soul is really joined to the whole body, and that we cannot properly say that it exists in any one part of the body to the exclusion of the others. For the body is a unity which is in a sense indivisible because of the arrangement of its organs, these being so related to one another that the removal of any one of them renders the whole body defective. And the soul is of such a nature that it has no relation to extension, or to the dimensions or other properties of the matter of which the body is composed: it is related solely to the whole assemblage of the body's organs. This is obvious from our inability to conceive of a half or a third of a soul, or of the extension which a soul occupies. Nor does the soul become any smaller if we cut off some part of the body, but it becomes completely separate from the body when we break up the assemblage of the body's organs” (AT XI:351, CSM I:339). But even though the soul is joined to the whole body, “nevertheless there is a certain part of the body where it exercises its functions more particularly ... which is a certain very small gland situated in the middle of the brain's substance and suspended above the passage through which the spirits in the brain's anterior cavities communicate with those in its posterior cavities. The slightest movements on the part of this gland may alter very greatly the course of these spirits, and conversely any change, however slight, taking place in the course of the spirits may do much to change the movements of the gland” (AT XI:351, CSM I:340).
hylomorphist: thinks that the soul is not a substance but the first actuality or substantial form of the living body
epiphenomenalist: views the passions as causally ineffectual by-products of brain activity

PINEAL GLAND TODAY:
The hormone secreted by the pineal gland, melatonin, was first isolated in 1958. Melatonin is secreted in a circadian rhythm, which is interesting in view of the hypothesis that the pineal gland is a vestigial third eye.
(Images from Google images search)
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